C. Shiga et al., ASSESSMENT OF NUTRITIONAL-STATUS OF POSTOPERATIVE-PATIENTS WITH BILIARY ATRESIA, Tohoku Journal of Experimental Medicine, 181(1), 1997, pp. 217-223
Some patients of biliary atresia (BA) suffer from chronic hepatic dysf
unction and/or persistent jaundice. The adverse effects of chronic liv
er disease on nutrition and growth should be considered on BA patients
. We studied 45 BA patients ranging in age from 0.5 to 38 years and di
vided them into 2 groups. Group A contains the patients whose total bi
lirubin greater than or equal to 2 mg/100 ml, and Group B contains the
patients whose total bilirubin < 2 mg/100 ml. We measured height, wei
ght, triceps skin fold (TSF), midarm circumference (MBC) and midarm mu
scle area (MAMA). Visceral protein kinetics was evaluated on the basis
of serum albumin and prealbumin levels. Caloric and protein intake wa
s calculated by collecting intake data for 3 days. The results of this
study were; 1) The mean TSF in Group B (47th percentile) was not sign
ificantly different from that in Group B (53th percentile). 2) The mea
n MAMA was significantly lower (p < 0.01) in Group A (16.4th percentil
e) than in Group B (36.7th percentile) 3) The prealbumin level was sig
nificantly lower (p < 0.001) in Group A (mean 9.9 mg/100 ml) than in G
roup B (mean 18.8 mg/100 ml). The authors conclude that the evaluation
of MAMA and prealbumin were very useful to characterize the low metab
olic status of protein in the damaged liver. And repeated nutritional
assessment was necessary to evaluate liver function and provide adequa
te nutrition in BE patients.