ADAPTATION OF INTESTINAL NUTRIENT TRANSPORT IN HEALTH AND DISEASE .2.

Citation
Abr. Thomson et G. Wild, ADAPTATION OF INTESTINAL NUTRIENT TRANSPORT IN HEALTH AND DISEASE .2., Digestive diseases and sciences, 42(3), 1997, pp. 470-488
Citations number
269
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
01632116
Volume
42
Issue
3
Year of publication
1997
Pages
470 - 488
Database
ISI
SICI code
0163-2116(1997)42:3<470:AOINTI>2.0.ZU;2-C
Abstract
The first part of this review dealt with the physiology of glucose tra nsport with specific emphasis on transporters of the brush border memb rane (BBM) and the basolateral membrane (BLM). On the BBM: the sodium (Na)/glucose transporters (SGLT1 and SGLT2), the Na-independent transp orter (GLUTS) and on the BLM the hexose transporter (GLUT2) are discus sed. The molecular biology of these transporters is also reviewed, In the second part of the review, we discuss the manner in which intestin al adaptation may be modified by alterations in the diet, especially t he lipid constituents, and two important examples of intestinal adapta tion will be given: diabetes mellitus and inflammatory bowel disease.