BREAST-CONSERVING TREATMENT FOR BREAST-CA NCER - ANALYSIS OF MORE THAN 1300 PATIENTS

From 1977 to 1994 a total of 1329 breast cancer patients have been tre ated with breast conserving surgery in the region of Basel, This analy sis is based on 832 patients treated from 1977 to 1990 according to a prospective treatment protocol, which was adjusted only once (1985), I n comparison with the most known international publications this analy sis represents one of the greatest homogeneous series of breast conser ving treatment, We observe an overall 5-year survival of 91% and a 10- year survival rate of 77 %, 94 % of the women remain locally recurrenc e free at 5 years and 86 % at 10 :years respectively, At 5 Sears, free dom of local recurrenc totals to 97 % in patients without (pN0) and to 89 % in patients with tumor involvement of the axillary lymph nodes ( pN+) (p = 0.00008), as well as to 96 % for pT1 and 91 % for pT2-tumors (p = 0.08328), In our analysis the K0 -resection significantly influe nces local recurrence free survival.