USEFUL INTERNAL STANDARDS FOR DISTINGUISHING INFILTRATIVE MARROW PATHOLOGY FROM HEMATOPOIETIC MARROW AT MRI

Citation
Kw. Carroll et al., USEFUL INTERNAL STANDARDS FOR DISTINGUISHING INFILTRATIVE MARROW PATHOLOGY FROM HEMATOPOIETIC MARROW AT MRI, Journal of magnetic resonance imaging, 7(2), 1997, pp. 394-398
Citations number
23
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
10531807
Volume
7
Issue
2
Year of publication
1997
Pages
394 - 398
Database
ISI
SICI code
1053-1807(1997)7:2<394:UISFDI>2.0.ZU;2-K
Abstract
The objective of this study was to establish internal standards on MRI differentiating infiltrative marrow pathology from hematopoietic marr ow, The T1-weighted images of 74 patients (51 biopsy-proven; 23 clinic al follow-up) were reviewed retrospectively The relative signal intens ity of bone marrow was compared to adjacent skeletal muscle (n = 65) a nd/or nondegenerated intervertebral disk (n = 53). Twenty foci were hy perintense compared to muscle, of which 17 (85%) cases represented nor mal red marrow (P < .0001); 45 were isointense or hypointense compared to muscle, of which 44 (98%) represented infiltrative marrow processe s (P < .0001), Twelve were hyperintense compared to disk, of which 12 (100%) represented normal red marrow (P < .0001); 41 were isointense o r hypointense compared to disk, of which 40 (98%) represented infiltra tive marrow processes (P .0001). On T1-weighted spin-echo MRI, skeleta l muscle and intervertebral disk may serve as internal standards for d ifferentiating infiltrative pathology from normal hematopoietic marrow , Marrow lesions that are relatively isointense or hypointense to musc le and/or disk should not be considered normal hematopoietic marrow.