The effects on serum lipids of palm oil (PA) used in Chinese diets wer
e compared with those of soybean oil (SO), peanut oil (PE) and lard (L
A) in normocholesterolemic subjects and with that of PE in hypercholes
terolemic subjects. Normocholesterolemic subjects [120 men, 18-25 y, t
otal cholesterol (TC) 2.8-5.0 mmol/L] were assigned to four groups to
consume test diets for six consecutive weeks after a run-in period of
3 wk. About 30% of dietary energy was derived from fat, 75-80% of whic
h came from test oils. In comparison with the entry level, the average
serum TC and LDL cholesterol (LDL-C) were 6.7 and 13.1% lower, respec
tively; in the PA group and 22.8 and 30.7% higher, respectively, (P <
0.05) in the LA group. At the end of the test, serum TC, LDL-C and the
ratio of TC/HDL cholesterol (HDL-C) in the PA group were significantl
y lower than those of the LA group. Hypercholesterolemic subjects (31
men, 20 women, 32-68 y, TC 5.5-7.0 mmol/L) were divided into two group
s. For 6 wk, one group (15 men, 10 women) consumed the PA diet; anothe
r group (16 men, 9 women) consumed the PE diet. After a 3-wk interval,
the two groups interchanged diets for another 6 wk. The test diets ag
ain contained about 30% energy from fat, 60-65% of which came from tes
t oils. Compared with entry values, the PA diet caused significant red
uctions in serum TC, LDL-C and TC/HDL-C during the first 6 wk and also
a significant reduction in TC/HDL-C during the second 6 wk, The PE di
et had no significant influence on serum lipids in either experimental
period.