METHANOL POISONING DURING LATE PREGNANCY

Citation
P. Hantson et al., METHANOL POISONING DURING LATE PREGNANCY, Journal of toxicology. Clinical toxicology, 35(2), 1997, pp. 187-191
Citations number
20
Categorie Soggetti
Toxicology
ISSN journal
07313810
Volume
35
Issue
2
Year of publication
1997
Pages
187 - 191
Database
ISI
SICI code
0731-3810(1997)35:2<187:MPDLP>2.0.ZU;2-L
Abstract
Case Report: A 26-year-old woman ingested 250 to 500 mL methanol durin g the 38th week of pregnancy. The initial serum methanol concentration was 230 mg/dL and formate was 33.6 mg/dL. A mild metabolic acidosis w as present. As gynecologic examination and fetal monitoring failed to detect fetal distress, it was decided to give tocolytic therapy until the treatment of methanol poisoning could be achieved in the mother. T herapy included ethanol infusion, bicarbonate administration and three courses of hemodialysis. Delivery occurred six days after methanol ex posure, when methanol was no longer detected in maternal blood. No fur ther complications were noted in the mother and her newborn. To our kn owledge, there is no other case of methanol poisoning during pregnancy in the literature.