NICKEL QUANTIFICATION IN MICE ORGANS BY ADSORPTIVE CATHODIC STRIPPINGVOLTAMMETRY USING MERCURY MICROELECTRODES

Mercury film microelectrodes (MFMs) were used to quantify trace levels of nickel accumulated in mice organs samples after dosing the mice wi th a physiological solution containing 150 ppm of Ni ions over a perio d of time, by performing adsorptive cathodic stripping square wave vol tammetry (AdSWV). The residues obtained after digestion of the biologi cal organs with nitric acid which affects the electrochemical response of Ni were investigated by XRD and IR spectrometry and found po be ma inly composed by p-nitrobenzoic acid. Electrochemical conditions for t he quantification of Niwith MFMs in the biological solutions were opti mized. The electrochemical data compared favorably with that obtained by atomic absorption spectrometry.