An unusual localization of intranasal angiomyolipoma is described in a
n adult male patient with no signs of tuberous sclerosis. The lesion w
as composed of mature fat cells, vascular spaces with lack of elastic
tissue, and presence of bundles of mature smooth muscle cells. Antibod
ies to intermediate filaments revealed presence of vimentin and absenc
e of desmin in both smooth muscle bundles and in vessel walls. A revie
w of the literature has shown that this is only the third reported cas
e of the angiomyolipoma of the nasal cavity, and some important differ
ences between this entity and renal angiomyolipoma are described. (C)
1994 John Wiley & Sons, Inc.