REGIONAL ASSIGNMENT OF GENETIC-MARKERS USING A SOMATIC-CELL HYBRID PANEL - A WWW INTERACTIVE PROGRAM AVAILABLE FOR THE PIG GENOME

Authors
CHEVALET C GOUZY J SANCRISTOBALGAUDY M
Citation
C. Chevalet et al., REGIONAL ASSIGNMENT OF GENETIC-MARKERS USING A SOMATIC-CELL HYBRID PANEL - A WWW INTERACTIVE PROGRAM AVAILABLE FOR THE PIG GENOME, Computer applications in the biosciences, 13(1), 1997, pp. 69-73
Citations number
7
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Computer Sciences, Special Topics","Computer Science Interdisciplinary Applications","Biology Miscellaneous
Journal title
Computer applications in the biosciences → ACNP
ISSN journal
02667061
Volume
13
Issue
1
Year of publication
1997
Pages
69 - 73
Database
ISI
SICI code
0266-7061(1997)13:1<69:RAOGUA>2.0.ZU;2-5
Abstract
Motivation: Quick and easy gene mapping by the use of a panel of cytog enetically characterized somatic cell hybrids is possible, even if som e discordant experimental results arise. Results: An interactive progr am is proposed and is made available on a WWW site to users of a somat ic cell hybrid panel. Assignments to chromosomes and subchromosomal re gions are based on likelihood calculations and Bayes' theorem, and a c onfidence level is provided. The method is illustrated in the case of the pig genome. Availability: The program can be accessed free of char ge at URL http://www.toulouse.inra.fr/lgc/lgc.html. Contact: E-mail: c hevalet@toulouse.inra.fr.