Interstitial laser coagulation (ILC) is a minimally invasive treatment
for benign prostatic hyperplasia (BPH). The objective of ILC is to in
duce shrinking of the prostate while preserving all surrounding tissue
s. To achieve thermal coagulation well inside the adenoma, not at its
urethral surface, laser radiation of a Nd : YAG laser or a diode laser
is transmitted by specially designed laser fibers. repeatedly placed
in the prostate tissue. This results in secondary atrophy and regressi
on of the prostate lobes, not sloughing of necrotic tissue. Since, Jul
y 1991, more than 800 patients have been treated in several studies. B
ased on initial experiences, many technical and procedural improvement
s of ILC have been introduced for clinical use, such as advanced radia
tion programs and new application devices including optical feedback s
ystems. Imaging studies demonstrated treatment effects and allowed fur
ther treatment optimization. Clinical studies have demonstrated the sa
fety and efficacy of ILC. This review summarizes several articles publ
ished on ILC and reports initial results of ongoing studies comparing
ILC and transurethral resection of the prostate (TURP).