SYNTHESIS OF BRIDGED 9-MEMBERED RING ETHERS - STUDIES DIRECTED TOWARDS THE SYNTHESIS OF EUNICELLIN-BASED MARINE DITERPENES

Authors
NOWAKOWSKI M HOFFMANN HMR
Citation
M. Nowakowski et Hmr. Hoffmann, SYNTHESIS OF BRIDGED 9-MEMBERED RING ETHERS - STUDIES DIRECTED TOWARDS THE SYNTHESIS OF EUNICELLIN-BASED MARINE DITERPENES, Tetrahedron, 53(12), 1997, pp. 4331-4338
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
12
Year of publication
1997
Pages
4331 - 4338
Database
ISI
SICI code
0040-4020(1997)53:12<4331:SOB9RE>2.0.ZU;2-M
Abstract
A concise annulation-fragmentation strategy has been elaborated for th e construction of the bridged nine-membered ring ether moiety of the e unicelline diterpenes. Key steps are a SmI2-induced Barbier cyclizatio n and an oxidative ring fission using cerium(IV) ammonium nitrate (CAN ). (C) 1997 Elsevier Science Ltd.