MEDICINAL FOODSTUFFS .5. MOROHEIYA .1. ABSOLUTE STEREOSTRUCTURES OF CORCHOIONOSIDE-A, CORCHOIONOSIDE-B, AND CORCHOIONOSIDE-C, HISTAMINE-RELEASE INHIBITORS FROM THE LEAVES OF VIETNAMESE CORCHORUS-OLITORIUS L (TILIACEAE)

Three new ionone glucosides named corchoionosides A, B, and C were iso lated from the leaves of Corchorus olitorius, commonly called ''morohe iya'' in Japanese, together with seven known compounds, an ionone gluc oside (6S,9R)-roseoside, a monoterpene glucoside betulalbuside A, two flavonol glucosides astragalin and isoquercitrin, two coumarin glucosi des scopolin and cichoriine, and chlorogenic acid. The absolute stereo structures of corchoionosides A, B, and C mere determined by chemical and physicochemical evidence, which included the result of application of a modified Mosher's method, the CD helicity rule, and chemical cor relation with (6S,9R)-roseoside. Corchoionosides A and B and (6S,9R)-r oseoside were found to inhibit the histamine release from rat peritone al exudate cells induced by antigen-antibody reaction.