RUTHENIUM COMPLEX-CATALYZED REACTION OF ISOCYANOACETATE AND N-SULFONYLIMINES - STEREOSELECTIVE SYNTHESIS OF N-SULFONYL-2-IMIDAZOLINES

Authors
LIN YR ZHOU XT DAI LX SUN J
Citation
Yr. Lin et al., RUTHENIUM COMPLEX-CATALYZED REACTION OF ISOCYANOACETATE AND N-SULFONYLIMINES - STEREOSELECTIVE SYNTHESIS OF N-SULFONYL-2-IMIDAZOLINES, Journal of organic chemistry, 62(6), 1997, pp. 1799-1803
Citations number
69
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
62
Issue
6
Year of publication
1997
Pages
1799 - 1803
Database
ISI
SICI code
0022-3263(1997)62:6<1799:RCROIA>2.0.ZU;2-W
Abstract
Ruthenium(II)-catalyzed reaction of N-sulfonylimines with methyl isocy anoacetate proceeds efficiently under neutral, mild conditions to give trans-2-imidazolines stereoselectively in high yields. 2,3-Diamino ac ids can be easily acquired via the hydrolysis of the imidazolines in e xcellent yields. A possible mechanism for the ruthenium-catalyzed aldo l reaction of the imines under neutral conditions is discussed.