We examined the effect of split-night polysomnography on compliance wi
th positive pressure via a mask for the treatment of obstructive sleep
-disordered breathing. A comparison of objective compliance (hours/day
) at the first meter read from the positive-pressure device (4-6 weeks
after set-up) in patients who had a successful split-night positive-p
ressure titration vs. patients who had traditional full-night positive
-pressure titration was performed. Patients were matched for age, sex,
and severity of the obstructive sleep-disordered breathing. Twelve pa
tients were matched with controls who underwent full-night polysomnogr
aphy. There were no significant differences between the split-night pa
tients and the full-night patients with regard to age, sex, body mass
index, and pretreatment Epworth Sleepiness Score. In addition, there w
as no significant difference between apnea-hypopnea index and the desa
turation-event frequency for both groups pre- and post-treatment. The
average daily use of continuous positive airway pressure (CPAP) at the
time of the first meter reading in the group that underwent full-nigh
t positive-pressure titrations as opposed to split-night titrations wa
s 5.2 hours/day +/- 2.2 vs. 3.8 hours/day +/- 2.9, respectively (p = 0
.29). The Epworth Sleepiness Scale on the initial clinic visit (as an
index of patient-perceived impairment) did not predict compliance at 4
-6 weeks. The time at the final positive pressure did not correlate wi
th compliance. Acceptance of positive pressure in the split-night pati
ents ranged from 62 to 67%.