A variety of oral appliances (OA) are now available for the treatment
of obstructive sleep apnea (OSA). OA therapy is effective in some pati
ents with mild to moderate OSA and is associated with greater patient
satisfaction than nasal CPAP. Adjustable OA are associated with improv
ed treatment success and fewer compliance failures compared to non-adj
ustable OA. Large randomized clinical trials are necessary to further
determine the precise indications, benefits, and risks of each OA in t
he treatment of OSA.