CYCLOPHOSPHAMIDE IN SEVERE STEROID-RESISTANT BRONCHIOLITIS OBLITERANSORGANIZING PNEUMONIA

Authors
PURCELL IF BOURKE SJ MARSHALL SM
Citation
If. Purcell et al., CYCLOPHOSPHAMIDE IN SEVERE STEROID-RESISTANT BRONCHIOLITIS OBLITERANSORGANIZING PNEUMONIA, Respiratory medicine, 91(3), 1997, pp. 175-177
Citations number
11
Categorie Soggetti
Cardiac & Cardiovascular System","Respiratory System
Journal title
Respiratory medicine → ACNP
ISSN journal
09546111
Volume
91
Issue
3
Year of publication
1997
Pages
175 - 177
Database
ISI
SICI code
0954-6111(1997)91:3<175:CISSBO>2.0.ZU;2-S
Abstract
A patient receiving carbamazepine and imipramine presented with severe bronchiolitis obliterans organizing pneumonia (BOOP). He developed pr ogressive respiratory failure in spite of high-dose steroid treatment. Cyclophosphamide was given as adjunctive therapy, and a rapid improve ment was seen. The authors suggest that an early therapeutic trial of cyclophosphamide should be considered in patients with BOOP who fail t o respond to steroids.