M. Thomsen et al., THE GOTTINGEN MINIPIG - A NEW ANIMAL-MODE L FOR TOTAL HIP-REPLACEMENT, Zeitschrift fur Orthopadie und Ihre Grenzgebiete, 135(1), 1997, pp. 58-62
The Gottingen mini swine is a good experimental animal. The electrolyt
es and the bone healing rate is comparable to human. The weight of the
animals should be 30-45 kg. All surgery is performed under endotrache
al general anaesthesia without any complication. There is minimal bloo
dless because blood pressure is only 40/80 mmHg. We used the anterolat
eral approach. The feature peculiarity of this animal modell are: 1. S
kin incision should start 10 cm cranial to the tail and should be curv
ed. 2. The osteotomy of the head is V-shaped in maximal external rotat
ion. 3. The acetabulum is prepared with a 23.5 mm reamer. 4. The stem
should be implanted first. After complesion of the preliminary testope
rations, 10 animals were operated in the described standard manner. Du
ring one year follow-up there was only one radiological cup-loosening.
The GMS is a simple animal modell for THR which could replace the dog
or the sheep.