PURPOSE: To determine the anatomic, hemodynamic, and radiologic charac
teristics of branch-vessel compromise in patients with aortic dissecti
on. MATERIALS AND METHODS: Sixty-two patients with aortic dissection w
ere evaluated with aortography (n = 62), intravascular ultrasound (US)
(n = 35), and manometry (n = 56). Branch-vessel compromise with ische
mia was suspected in 40 of these patients. Radiologic and manometric f
indings were correlated with clinical findings of ischemia. Femoral ar
tery pulse strength was correlated with access from the respective fem
oral artery to the true and false lumina of the dissected aorta. RESUL
TS: Twenty-six of 40 patients suspected of having ischemia had angiogr
aphic evidence of branch-vessel compromise, and intravascular US helpe
d identify two types of branch-vessel compromise in them: static (diss
ection intersected and narrowed the vessel origin) and dynamic (dissec
tion spared the vessel origin, but the dissection flap appeared to com
press the true lumen at or above the origin and covered the origin). F
alse-lumen pressure in classic dissections exceeded (n = 16) or equale
d (n = 30) true-lumen pressure. Branch vessels that arose exclusively
from the false lumen were well perfused. Findings of a dissection flap
oriented concave toward the false lumen were 91% sensitive and 72% sp
ecific for a true-lumen pressure deficit. CONCLUSION: Intravascular US
and manometric findings clarify the mechanisms of branch-vessel compr
omise after aortic dissection and provide a rational guide for percuta
neous treatment.