We investigated the olfactory evoked magnetic fields (OEFs) in 14 norm
al subjects. Pulses of odorant air containing amyl acetate or phenethy
l alcohol, and odorless air were administered to the subject through a
nasal tube. A clear and consistent OEF component, 1M, was identified
in all subjects, and a second component, 2M, was detected in seven sub
jects, but no consistent component was identified in response to the o
dorless air. The peak latencies of the 1M and 2M components were appro
ximately 320 and 630 ms, respectively. The waveforms produced by the o
dorless air were subtracted from the waveforms produced by the odorant
air to obtain the 'subtraction' waveform, which indicated the 1M and
2M component more clearly. Their equivalent current dipoles (ECDs) wer
e estimated in the regions around the Sylvian fissure symmetrically in
both hemispheres. Therefore, these areas are proposed to be involved
in olfactory perception in humans. (C) 1997 Elsevier Science Ireland L
td.