INCREASED SERUM LEUKOTRIENE B-4 LEVEL IN THE ACTIVE STAGE OF RHEUMATOID-ARTHRITIS IN CHILDREN

Citation
T. Gursel et al., INCREASED SERUM LEUKOTRIENE B-4 LEVEL IN THE ACTIVE STAGE OF RHEUMATOID-ARTHRITIS IN CHILDREN, Prostaglandins, leukotrienes and essential fatty acids, 56(3), 1997, pp. 205-207
Citations number
11
Categorie Soggetti
Endocrynology & Metabolism",Biology
ISSN journal
09523278
Volume
56
Issue
3
Year of publication
1997
Pages
205 - 207
Database
ISI
SICI code
0952-3278(1997)56:3<205:ISLBLI>2.0.ZU;2-0
Abstract
The possible association of leukotriene B-4 (LTB(4))-like activity wit h the development of active rheumatoid arthritis was studied in 25 chi ldren with the disease and in 15 normal subjects. Serum LTB,-like acti vity was found to be significantly higher in the active stage of the d isease when compared with the values obtained from patients during the inactive stage and from healthy children. No correlation was found be tween LTB(4)-activity and other laboratory parameters, e.g. haemoglobi n level, white cell count and erythrocyte sedimentation rate.