ATTEMPTS TO USE LIPOSOMES AND RBC GHOSTS AS VECTORS IN DRUG AND ANTISENSE THERAPY OF VIRUS-INFECTION

Citation
S. Grimaldi et al., ATTEMPTS TO USE LIPOSOMES AND RBC GHOSTS AS VECTORS IN DRUG AND ANTISENSE THERAPY OF VIRUS-INFECTION, Research in virology, 148(2), 1997, pp. 177-180
Citations number
13
Categorie Soggetti
Virology
Journal title
ISSN journal
09232516
Volume
148
Issue
2
Year of publication
1997
Pages
177 - 180
Database
ISI
SICI code
0923-2516(1997)148:2<177:ATULAR>2.0.ZU;2-4
Abstract
Selective targeting of drugs or oligonucleotide for the treatment of v iral diseases or cancer is the objective of new strategies that pursue therapy optimization and reduction of toxicity. In this work we repor t two protocols based on encapsulation of antihuman immunodeficiency v irus drugs within targeted liposomes or erythrocytes. Both have been s hown to be effective for the specific delivery of drugs or oligonucleo tide in the treatment of viral infection.