COLORECTAL-CANCER - CLINICAL AND PATHOLOGICAL FEATURES

Despite an improved understanding of the pathogenesis of colorectal ca ncer and the technical ability to alter its natural history in a large proportion of average and high-risk patients, this cancer remains dea dly. There has been no significant change in incidence or survival rat es over the past 40 years. This indicates a continued need for earlier detection of polyps and cancers, aggressive surgery for the primary t umor, and improved multimodality treatment for metastatic disease.