Objectives: To compare the effect of four types of thigh-length gradua
ted compression stockings (GCS) on lower limb venous blood flow using
strain-gauge plethysmography (SGP). Design: A randomized controlled st
udy. Setting: Inpatient Orthopaedic Centre. Patients: 200 preoperative
patients admitted for elective lower limb orthopaedic surgery. Interv
entions: Patients were randomized to five groups to wear one of four t
ypes of GCS or no stocking (control). Resting venous flow parameters w
ere measured prior to application of GCS and after 20 min bed rest wit
h the stockings in situ. Main outcome measures: Effects on resting ven
ous capacitance (Vc) and venous outflow (Vo). Results: In the control
group 20 min bed rest had no effect on the parameters studied. Both Vc
and Vo were significantly increased (p<0.001) in all the groups weari
ng stockings. There was a significant variation in the changes in outf
low produced by the different stocking types (p<0.05). Conclusions: GC
S have a beneficial effect on lower limb venous outflow, preventing ve
nous stasis, an important factor in the development of deep venous thr
ombosis. This effect varies depending on which type of stocking is use
d.