IMMOBILIZATION OF ENZYMES ON METHACRYLAMIDE-BASED COPOLYMERS

A series of reactive polymeric supports for the covalent binding of en zymes was prepared from methacrylamide in conjunction with various cop olymerized monomers. In all cases the specific surface area of the pre pared copolymer particles increased with the ratio of crosslinker to m onomer. The polymers containing oxirane and aldehyde groups were promi sing for direct binding of beta-galactosidase, whereas the supports co ntaining amino groups also qualified for enzyme immobilization with gl utaraldehyde.