SEPTO-OPTIC DYSPLASIA ASSOCIATED WITH CEREBRAL CORTICAL DYSPLASIA (CORTICO-SEPTO-OPTIC DYSPLASIA)

It is generally accepted that there are two subsets of septo-optic dys plasia (deMorsier's syndrome), one with schizencephaly and the other w ithout schizencephaly. A third form of the anomaly which is associated with callosal absence has also been described. Except for schizenceph aly, the association of septo-optic dysplasia with another major type of disorder of neuronal migration and organization such as cortical dy splasia, has not yet been reported. We report the MR imaging examinati on of a 3-year-old patient with bilateral rolandic cortical dysplasia, and with apparent thinning of the optic nerves, and absent septum pel lucidum (septo-optic dysplasia) as a new combination. This can be labe lled as cortico-septooptic dysplasia.