ADVANCES IN MICROBIAL STEROID BIOTRANSFORMATION

Microbial biotransformations of various steroids are reviewed. Develop mental studies on hydroxylation, carbon-carbon bond cleavage, enzymati c catalysis in nonaqueous solvents, use of cyclodextrin medium, cell i mmobilization, and new microbial reactions are highlighted. Various st eroid substrates, their metabolites and the microorganisms used for th e transformations are compiled covering the literature for the period 1992-1995. (C) 1997 by Elsevier Science Inc.