ELECTROPHYSIOLOGIC PROPERTIES OF THE ADULT HUMAN SINUS NODE

Electrophysiology of the Human SA Node. Electrophysiologic properties of the sinoatrial (SA) node have been studied extensively in various s pecies, Published studies on human SA nodal properties were carried ou t on fetal SA node preparations; however, the electrophysiologic prope rties of adult human cardiac tissues have never been examined, Tn this study we report, for the first time, recordings of transmembrane pote ntials in the adult human SA node, Our data demonstrate that the elect rical behavior of adult human SA node pacemaker cells resemble those o f SA nodal tissue of different animal species, We conclude that the la tter ideally mimic the former, Furthermore, human SA node preparations could contribute to a better understanding of some sinus arrhythmias.