Objectives: Rapid cycling mood disorder is an important clinical pheno
menon. The concept of rapid cycling has evolved since it was first des
cribed in 1974. The purpose of this review is to summarise current dia
gnostic criteria, postulated risk factors and suggested management str
ategies. Method: A Medline and Psych-Lit computerised literature searc
h was supplemented by tracing back through the references from existin
g review work. Results: Over 80 papers were identified which discussed
diagnosis and management of rapid cycling. Conclusions: DSM-IV provid
es a useful but narrow definition of rapid cycling. Standard treatment
of affective disorder may exacerbate rapid cycling. If a rapid cyclin
g course develops, discontinuation of antidepressants and use of mood
stabilisers is recommended.