DESIGN OF NEW HOST COMPOUNDS, 1,3-DIPHENYLCYCLOHEXANE-1,3-DIOL, 1,4-BIS(HYDROXYDIPHENYLMETHYL)CYCLOHEXANES, 1,3-BIS(HYDROXYDIPHENYLMETHYL)CYCLOHEXANES, AND 1,2-BIS(HYDROXYDIPHENYLMETHYL)CYCLOHEXANES, AND 1,2-BIS(HYDROXYDIPHENYLMETHYL)CYCLOPROPANE

The title host compounds were designed. The cis-1,3-diphenylcyclohexan e-1,3-diol, its 2-methyl derivative, as well as the cis- and tuans-iso mers of 1,4- and 1,3-bis (hydroxydiphenylmethyl) cyclohexanes showed h igh inclusion ability for guest compounds. However, while the trans-1, 2-bis(hydroxydiphenylmethyl)cyclopropane showed also a good inclusion ability, cis-1,2-bis(hydroxydiphenylmethyl)cyclohexane showed none. In order to evaluate the structural features which control the inclusion behavior of the newly designed host compounds, molecular and crystal structures of inclusion complexes of trans-1,4-bis(hydroxydiphenylmeth yl)cyclohexane with acetone and with MeOH, and of cis-1,3-diphenylcycl ohexane-1,3-diol with EtOH were determined.