Jhy. Vilegas et al., DETERMINATION OF COUMARIN AND KAURENOIC ACID IN MIKANIA-GLOMERATA (GUACO) LEAVES BY CAPILLARY GAS-CHROMATOGRAPHY, Phytochemical analysis, 8(2), 1997, pp. 74-77
capillary gas chromatography procedure for the determination of coumar
in and kaurenoic acid in 'guaco' (Mikania glomerata Spreng., Composita
e) leaves is described. The method is shown to be sensitive and reprod
ucible. The contents of coumarin and kaurenoic acid in a sample of 'gu
aco' from Ribeirao Preto (Brazil) were found to be 4.40(+/-0.21) and 2
.00 (+/-0.06) mg/g dried plant material, respectively. The method may
have application in the analysis of 'guaco' crude drug. (C) 1997 by Jo
hn Wiley & Sons, Ltd.