CYSTIC SQUAMOUS-CELL CARCINOMAS IN THE LUNGS OF SYRIAN GOLDEN-HAMSTERS INDUCED BY COAL OVEN FLUE EXHAUST MIXED WITH PYROLIZED TAR PITCH IN COMBINATION WITH BENZO(A)PYRENE

Authors
RITTINGHAUSEN S DUNGWORTH DL DASENBROCK C ERNST H MOHR U
Citation
S. Rittinghausen et al., CYSTIC SQUAMOUS-CELL CARCINOMAS IN THE LUNGS OF SYRIAN GOLDEN-HAMSTERS INDUCED BY COAL OVEN FLUE EXHAUST MIXED WITH PYROLIZED TAR PITCH IN COMBINATION WITH BENZO(A)PYRENE, Experimental and toxicologic pathology, 49(1-2), 1997, pp. 11-14
Citations number
24
Categorie Soggetti
Pathology,Toxicology
Journal title
Experimental and toxicologic pathology → ACNP
ISSN journal
09402993
Volume
49
Issue
1-2
Year of publication
1997
Pages
11 - 14
Database
ISI
SICI code
0940-2993(1997)49:1-2<11:CSCITL>2.0.ZU;2-M
Abstract
Among a variety of induced pulmonary tumours, cystic squamous cell car cinomas were observed in five Syrian hamsters that inhaled a mixture o f pyrolized tar pitch with coal oven flue exhaust (PCE) and additional ly received intratracheal injections of benzo(a)pyrene. The histologic al appearance of these particular tumours is described, compared to si milar tumour types in rats and the susceptibility of both species to i nert particles is discussed.