A. Villegasnavarro et al., LEAD CONCENTRATION IN DIFFERENT COMPARTMENTS OF THE BOVINE EYE, Experimental and toxicologic pathology, 49(1-2), 1997, pp. 87-90
It is known that lead is a metabolic substitute of calcium and recentl
y, in vitro results showed that glycosaminoglycans and proteins are ca
pable of binding lead. Therefore, in this work, the level of lead in a
queous humor, vitreous humor, lens and sclera of bovine eyes was analy
zed in order to establish a relationship between lead concentration an
d the contents of glycosaminoglycans, proteins, water and calcium in t
hose structures. Lead was determined by means of atomic absorption spe
ctrometry after acid digestion. Our results suggest a direct relations
hip between the contents of proteins and glycosaminoglycans, and the a
bility of the different eye structures to retain lead. Nevertheless, a
n inverse relationship between water content and lead concentration wa
s found. No association between calcium and lead concentrations was ob
served.