ACYLATION OF 3-BETA-(2-HYDROXYETHOXY)CHOL EST-5-ENE IN THE PRESENCE OF LECITHIN-CHOLESTEROL ACYLTRANSFERASE FROM BLOOD-PLASMA

Authors
MALYUGIN AV MEDVEDEVA NV MISHARIN AY
Citation
Av. Malyugin et al., ACYLATION OF 3-BETA-(2-HYDROXYETHOXY)CHOL EST-5-ENE IN THE PRESENCE OF LECITHIN-CHOLESTEROL ACYLTRANSFERASE FROM BLOOD-PLASMA, Bioorganiceskaa himia, 23(1), 1997, pp. 75-77
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
23
Issue
1
Year of publication
1997
Pages
75 - 77
Database
ISI
SICI code
0132-3423(1997)23:1<75:AO3EIT>2.0.ZU;2-3
Abstract
3 beta-(2-Hydroxyethoxy)cholest-5-ene in the composition of the micell ar complexes with apolipoprotein A1 and palmitoyloleoylphosphatidylcho line was acylated in the presence of lecithin-cholesterol acyltransfer ase from human plasma. The initial rate of acylation was 6-8 times low er than the rate of cholesterol acylation under the same conditions. T he presence of 3 beta-(2-hydroxyethoxy)cholest-5-ene did not affect th e rate of the enzymic acylation of cholesterol.