CHARACTERIZATION OF THE ESCHERICHIA-COLI GENE ENCODING A NEW MEMBER OF THE SHORT-CHAIN DEHYDROGENASE REDUCTASE (SDR) FAMILY/

Authors
SIRKO A WEGLENSKA A HRYNIEWICZ M HULANICKA DM
Citation
A. Sirko et al., CHARACTERIZATION OF THE ESCHERICHIA-COLI GENE ENCODING A NEW MEMBER OF THE SHORT-CHAIN DEHYDROGENASE REDUCTASE (SDR) FAMILY/, Acta Biochimica Polonica, 44(1), 1997, pp. 153-157
Citations number
16
Categorie Soggetti
Biology
Journal title
Acta Biochimica Polonica → ACNP
ISSN journal
0001527X
Volume
44
Issue
1
Year of publication
1997
Pages
153 - 157
Database
ISI
SICI code
0001-527X(1997)44:1<153:COTEGE>2.0.ZU;2-H
Abstract
The nucleotide sequence of a chromosomal DNA fragment located upstream from the cysPTWAM operon of Escherichia coil was established. Sequenc e analysis indicates the presence of an open reading frame which has b een designated ucpA (upstream cysP). The potential protein product exh ibits strong sequence homology to the members of a large protein famil y, short-chain dehydrogenases/reductases. Involvement of Crp, FruR and IHF in the regulation of ucpA transcription in vivo was demonstrated.