Mj. Malkowski et al., THE MORPHOLOGIC CHARACTERISTICS OF FLAIL MITRAL LEAFLETS BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY, Journal of heart valve disease, 6(1), 1997, pp. 54-59
Background and aims of the study: Mitral valve prolapse due to floppy
mitral valve (MVP/FMV) is a common valvular abnormality with a variabl
e clinical course. Flail mitral valve leaflet resulting in severe mitr
al regurgitation is a complication of MVP/FMV. Methods: In order to un
derstand the structural correlates of flail mitral valve leaflet in MV
P, we reviewed the morphologic characteristics of the mitral valve by
transesophageal echocardiography (TEE) in 72 patients (24 normal; 26 m
itral valve prolapse; 22 flail mitral valve leaflet). Results: Compare
d with the normal group, the mitral valve prolapse group had greater a
nterior and posterior mitral valve leaflet thickness and anterior mitr
al valve leaflet length. Patients with flail mitral valve leaflets as
a complication of FMV had greater anterior and posterior mitral valve
leaflet length and posterior mitral valve leaflet thickness compared w
ith MVP patients without flail mitral valve leaflets. Posterior mitral
valve leaflet length was the only echocardiographic independent predi
ctor of flail mitral valve leaflet. Older FMV patients with increased
mitral valve leaflet length and thickness are predisposed to flail mit
ral valve leaflets and severe mitral regurgitation. Conclusions: TEE m
ay identify patients with MVP/FMV with the greatest structural abnorma
lities who are at risk for complications such as flail mitral valve le
aflet(s).