Hemolytic anemia is a well-recognized complication of mechanical heart
valve prosthesis but, as yet, has not been reported after mitral valv
e repair with chordal replacement. We report a case of severe hemolyti
c anemia after mitral valve repair with chordal replacement and Carpen
tier-Edwards annuloplasty ring insertion. Progressive prolapse of the
anterior leaflet due to the artificial chordae being too long caused r
ecurrent regurgitation which was responsible for the hemolysis. The pa
tient also had idiopathic thrombocytopenic purpura, but successful sec
ond mitral valve repair was performed after high-dose gamma-globulin t
herapy.