A CONVENIENT AUTOMATED SOLID-PHASE SYNTHESIS OF PNA-(5')-DNA-(3')-PNACHIMERA

Authors
VANDERLAAN AC BRILL R KUIMELIS RG KUYLYEHESKIELY E VANBOOM JH ANDRUS A VINAYAK R
Citation
Ac. Vanderlaan et al., A CONVENIENT AUTOMATED SOLID-PHASE SYNTHESIS OF PNA-(5')-DNA-(3')-PNACHIMERA, Tetrahedron letters, 38(13), 1997, pp. 2249-2252
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
13
Year of publication
1997
Pages
2249 - 2252
Database
ISI
SICI code
0040-4039(1997)38:13<2249:ACASSO>2.0.ZU;2-8
Abstract
An automated online solid-phase synthesis of Ac-cac ct TGG TC t*ac ct -Gly-OH1 using standard DNA and appropriately protected PNA building b locks (2-5) is described. This chimera forms stable duplexes with comp lementary DNA and RNA. (C) 1997 Elsevier Science Ltd.