STEREOSELECTIVE SYNTHESIS OF A FUNCTIONALIZED BICYCLIC CORE OF NEOCARZINOSTATIN AND KEDARCIDIN CHROMOPHORES

Authors
CADDICK S DELISSER VM
Citation
S. Caddick et Vm. Delisser, STEREOSELECTIVE SYNTHESIS OF A FUNCTIONALIZED BICYCLIC CORE OF NEOCARZINOSTATIN AND KEDARCIDIN CHROMOPHORES, Tetrahedron letters, 38(13), 1997, pp. 2355-2358
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
13
Year of publication
1997
Pages
2355 - 2358
Database
ISI
SICI code
0040-4039(1997)38:13<2355:SSOAFB>2.0.ZU;2-Y
Abstract
The stereoselective synthesis of a bicyclic ring system related to Neo carzinostatin and Kedarcidin Chromophores is described; key steps invo lve stereoselective conjugate addition of an enediyne to an enone and intramolecular aldol reaction of a cobalt complexed alkynyl aldehyde. (C) 1997 Elsevier Science Ltd.