The choice of antidepressant is largely governed by its side-effect pr
ofile. The predictable and idiosyncratic adverse effects of tricyclic
antidepressants, selective serotonin re-uptake inhibitors, monoamine o
xidase inhibitors and atypical antidepressants are discussed. Informat
ion on the newer agents, such as citalopram, milnacipran, mirtazapine,
nefazodone and venlafaxine, is included.