POLYMERIZATION OF THE 12-METHACRYLOYLOXYDODECANOIC ACID AND A CORRESPONDING PHOSPHOLIPID IN MONOLAYERS AT THE LIQUID GAS INTERFACES/

The following surface-active monomers with methacrylic group at the en d of hydrophobic tail: 12-methacryloyloxydodecanoic acid (12-MAODA) an d hacryloyloxydodecanoyl)-glycerophosphatidylcholine 12-MAODPC) were s ynthesized and investigated. Both monomers are forming monolayers at t he liquid/gas interfaces with liquid-expanded and liquid-condensed sta tes at low and high surface pressures, respectively. These monomers ha ve been polymerized in the monolayers just by soft UV-irradiation (254 nm). Dependences of polymerization rate vs. surface pressure for both monomers have maxima (3.3310(-4) s(-1) for 12-MAODPC and 4.89*10(-4) s(-1) for 12-MAODA) at about 8 - 10 mN/m. The higher polymerizarion r ate of 12-MAODA polymerization as compared to 12-MAODPC is due to the more dense packing of the acid molecules in monolayers as compared to the lipid. Areas per monomer unit in the obtained polymeric monolayers are much smaller than those for the monomer one. The collapse pressur es increase after monomer polymerization that evidences the increase o f the monolayer stability in case of polymer as compared to monomer.