CYCLODEXTRINS AS HOSTS FOR POORLY WATER-SOLUBLE COMPOUNDS IN ENZYME CATALYSIS

Authors
BRU R LOPEZNICOLAS JM NUNEZDELICADO E NORTESRUIPEREZ D SANCHEZFERRER A GARCIACARMONA F
Citation
R. Bru et al., CYCLODEXTRINS AS HOSTS FOR POORLY WATER-SOLUBLE COMPOUNDS IN ENZYME CATALYSIS, Applied biochemistry and biotechnology, 61(1-2), 1996, pp. 189-198
Citations number
28
Categorie Soggetti
Biothechnology & Applied Migrobiology",Biology
Journal title
Applied biochemistry and biotechnology → ACNP
ISSN journal
02732289
Volume
61
Issue
1-2
Year of publication
1996
Pages
189 - 198
Database
ISI
SICI code
0273-2289(1996)61:1-2<189:CAHFPW>2.0.ZU;2-2
Abstract
The capability of cyclodextrins to enhance greatly the solubility in w ater of poorly water-soluble substances makes them an ideal alternativ e for investigating the expression of enzyme activity with such substr ates in aqueous solution. This capability is demonstrated by using soy bean lipoxygenase with linoleic acid/beta-cyclodextrin and diethylstil bestrol/gamma-cyclodextrin, and cholesterol oxidase with cholesterol/m ethyl-beta-cyclodextrin.