INTRASPINAL HIGH-GRADE ASTROCYTOMA IN A CHILD - RATIONALE FOR CHEMOTHERAPY AND MORE INTENSIVE RADIOTHERAPY

Authors
WEISS E KLINGEBIEL T KORTMANN RD HESS CF BAMBERG M
Citation
E. Weiss et al., INTRASPINAL HIGH-GRADE ASTROCYTOMA IN A CHILD - RATIONALE FOR CHEMOTHERAPY AND MORE INTENSIVE RADIOTHERAPY, Child's nervous system, 13(2), 1997, pp. 108-112
Citations number
42
Categorie Soggetti
Clinical Neurology",Pediatrics
Journal title
Child's nervous system → ACNP
ISSN journal
02567040
Volume
13
Issue
2
Year of publication
1997
Pages
108 - 112
Database
ISI
SICI code
0256-7040(1997)13:2<108:IHAIAC>2.0.ZU;2-8
Abstract
Intraspinal high-grade astrocytoma in children is an extremely rare tu mor entity with disappointingly short survival times despite multimoda lity treatment. We report on a girl with anaplastic astrocytoma at lev el T9-11, who was treated with tumor resection, multidrug chemotherapy and irradiation. Local recurrence was diagnosed after 16 months. With reference to other cases reported in the literature, the course of di sease, achievements and limitations of currently available therapeutic options, and potential future strategies are discussed.