M. Hosono et al., SEPTUM-LIKE STRUCTURES IN LIPOMA AND LIPOSARCOMA - MR-IMAGING AND PATHOLOGICAL CORRELATION, Skeletal radiology, 26(3), 1997, pp. 150-154
Objective. To-investigate the septum-like structures in predominantly
lipomatous tumors, by correlating fat-suppressed MR images with histop
athologic findings. Design and patients. The MR findings of three case
s of well-differentiated liposarcoma (atypical lipoma), one case of li
poma-like component of dedifferentiated liposarcoma. and nine cases of
lipoma were analyzed. T1-, T2-, and fat-suppressed T1- weighted image
s after Gd-DTPA administration were obtained. Surgical specimens from
five patients (four with liposarcoma and one with lipoma) were also sc
anned with a MR unit, and compared with the pathologic findings. Resul
ts and conclusions. Enhancement features of lipoma and liposarcoma wer
e well visualized on fat-suppressed T1-weighted images after Gd-DTPA a
dministration. The septum-like structures of liposarcoma are thick and
enhanced considerably, while septa of lipoma are thin and enhanced on
ly slightly. Pathologically, the septum-like structures of Liposarcoma
contained muscle fibers and the septa of lipoma represented fibrous c
apsule, Identification of well-enhanced septa in a predominantly lipom
atous tumor helps to differentiate malignant tumors horn lipomas. As t
he septum-like structures of liposarcoma contain a skeletal muscle com
ponent the tumor might need more extensive surgical procedures includi
ng resection of adjacent muscles.