A Coulomb sum rule is derived for the response of nuclei to (e, e') sc
attering with large three-momentum transfers. Unlike the nonrelativist
ic formulation, the relativistic Coulomb sum is restricted to spacelik
e four-momenta for the most direct connection with experiments; an imm
ediate consequence is that excitations involving antinucleons, e.g., N
NBAR pair production, are approximately eliminated from the sum rule.
Relativistic recoil and Fermi motion of target nucleons are correctly
incorporated. The sum rule decomposes into one- and two-body parts, w
ith correlation information in the second. The one-body part requires
information on the nucleon momentum distribution function, which is in
corporated by a moment expansion method. The sum rule given through th
e second moment (RCSR-II) is tested in the Fermi gas model, and is sho
wn to be sufficiently accurate for applications to data.