SPRAY-PYROLYSIS PREPARATION OF APATITE-COMPOSITE PARTICLES FOR BIOLOGICAL APPLICATION

Apatite derived by sol-gel routes through an amorphous state or derive d biomimetically is likely to provide chemically and biologically acti ve surfaces. Thus apatite or apatite-composite particles were prepared by spray-pyrolysis of several solutions as they were applicable to me dical treatment. Calcium lactate and ammonium dihydrogen phosphate aqu eous solutions stabilized with ethylenediaminetetraacetic acid were sp rayed ultrasonically and pyrolysed at 600 degrees C to yield amorphous particles of apatite while apatite-ferric oxide composite powders wer e prepared from the solutions of calcium lactate and ferric nitrate. S olutions of calcium nitrate and titanium ethoxide in 0.5 N HNO3 were a lso spray-pyrolysed at 600 degrees C to prepare calcium titanate and t itanium oxide particles trapped on a Ti substrate. Apatite could biomi metically be developed on the calcium titanate particles when they wer e soaked in an acellular simulated body fluid.