A. Osaka et al., SPRAY-PYROLYSIS PREPARATION OF APATITE-COMPOSITE PARTICLES FOR BIOLOGICAL APPLICATION, JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 8(1-3), 1997, pp. 655-661
Apatite derived by sol-gel routes through an amorphous state or derive
d biomimetically is likely to provide chemically and biologically acti
ve surfaces. Thus apatite or apatite-composite particles were prepared
by spray-pyrolysis of several solutions as they were applicable to me
dical treatment. Calcium lactate and ammonium dihydrogen phosphate aqu
eous solutions stabilized with ethylenediaminetetraacetic acid were sp
rayed ultrasonically and pyrolysed at 600 degrees C to yield amorphous
particles of apatite while apatite-ferric oxide composite powders wer
e prepared from the solutions of calcium lactate and ferric nitrate. S
olutions of calcium nitrate and titanium ethoxide in 0.5 N HNO3 were a
lso spray-pyrolysed at 600 degrees C to prepare calcium titanate and t
itanium oxide particles trapped on a Ti substrate. Apatite could biomi
metically be developed on the calcium titanate particles when they wer
e soaked in an acellular simulated body fluid.