Citation
Je. Hochlowski et al., PRODUCTION OF BROMINATED TIACUMICIN DERIVATIVES, Journal of antibiotics, 50(3), 1997, pp. 201-205
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
ISSN journal
00218820
Volume
50
Issue
3
Year of publication
1997
Pages
201 - 205
Database
ISI
SICI code
0021-8820(1997)50:3<201:POBTD>2.0.ZU;2-A
Abstract
Several novel tiacumicin derivatives containing bromine have been prod
uced by the addition of inorganic bromine to the fermentation broth of
Dactylosporangium aurantiacum subsp. hamdenensis. Structures were elu
cidated employing mass spectrometry and NMR spectroscopy. Antibacteria
l activity of the bromotiacumicins is comparable to that of the parent
compounds.