EVIDENCE THAT PRESYNAPTIC CHANGES ARE INVOLVED IN THE EXPRESSION OF LTP AND LTD OF NMDA RECEPTOR-MEDIATED EPSCS IN AREA CA1 OF THE HIPPOCAMPUS

Authors
CLARK KA COLLINGRIDGE GL
Citation
Ka. Clark et Gl. Collingridge, EVIDENCE THAT PRESYNAPTIC CHANGES ARE INVOLVED IN THE EXPRESSION OF LTP AND LTD OF NMDA RECEPTOR-MEDIATED EPSCS IN AREA CA1 OF THE HIPPOCAMPUS, J PHYSL-PAR, 90(5-6), 1996, pp. 311-311
Citations number
5
Categorie Soggetti
Physiology,Neurosciences
Journal title
JOURNAL OF PHYSIOLOGY-PARIS
ISSN journal
09284257 → ACNP
Volume
90
Issue
5-6
Year of publication
1996
Pages
311 - 311
Database
ISI
SICI code
0928-4257(1996)90:5-6<311:ETPCAI>2.0.ZU;2-N
Abstract
Plasticity of NMDA receptor-mediated synaptic transmission was studied in the CAI region of the hippocampus utilising whole cell patch-clamp recording techniques. LTP was associated with a decrease in CV wherea s LTD was accompanied by an increase in CV and a decrease in Pr. These data are consistent with LTP and LTD being an opposite expression of the same fundamental process.