Nj. Emptage et al., PHARMACOLOGICAL DISSOCIATION OF DIFFERENT FORMS OF SYNAPTIC PLASTICITY IN THE MARINE MOLLUSK APLYSIA, J PHYSL-PAR, 90(5-6), 1996, pp. 385-386
The actions of the neuromodulator serotonin (5HT) in Aplysia sensory n
eurons can be dissociated on the basis of their sensitivity to the 5HT
receptor antagonist cyproheptadine, and their concentration requireme
nt to 5HT. Here we summarise a series of experiments that suggest that
mechanistically distinct processes contribute to the different physio
logical components of short- and long-term synaptic plasticity.