Neurofibromatosis type 1 (NF1) in children can produce a variety of pa
renchymal signal abnormalities on cranial MR, Areas of abnormal signal
in these patients may represent regions of disordered myelination, ''
hamartomatous'' change or frank neoplasia. The presence of contrast en
hancement in intracranial lesions in patients with NF1 is usually stro
ngly suggestive of tumor. We report the case of a child with NF1 and a
focal enhancing brain parenchymal lesion which spontaneously resolved
without specific therapy.