The applicability of an image guidance frameless system based on an op
to-electronic sensor device in skull base surgery was explored in this
study. Five embalmed heads with external fiducial markers placed in n
oncoplanar points were scanned (CT scan) and different skull base appr
oaches were reproduced in these specimens. The opto-electronic system
is comprised of an infrared cameral a local rigid body, and a 24-light
-emitting diode probe attached to different surgical instruments. DOS-
based calibration and transformation software and Unix-based surgical
planning software were also used. The anatomic landmarks identified du
ring the dissection were matched with the corresponding points derived
from computed tomographic (CT) scans. This information allowed the su
rgeon to develop a three dimensional representation of the surgical fi
eld and to anticipate the next anatomic structure encountered during t
he dissection. This infrared device operated in real time, is not affe
cted by external factors with regard to its accuracy, and does not int
erfere with standard neurosurgical techniques. This frameless system i
s helpful in minimizing the risk of morbidity and provides an accurate
guide during the approach, as well as unobstructed access to the surg
ical field.